1,6-Hexanedithiol (HDT) is a versatile molecule with a wide range of applications in a variety of industries. It is a bi-functional alkanethiol with a linear and zig-zag structure that consists of 6 carbon atoms in a tetrahedral configuration. HDT is used to form a self-assembled monolayer (SAM) on many different substrates, providing a stable and uniform surface for further functionalization and immobilization of the surface atoms.

1,6 hexanedithiol

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Chemical Uses


1,6-Hexanedithiol (HDT) is an organic compound used as a building block in organic chemistry. It is a long-chained bi-functional alkanethiol, with 6 carbon atoms arranged in a zig-zag pattern, and forms a tetrahedral configuration. HDT is a versatile tool for immobilizing surface atoms of a variety of substrates, either through self-assembly or covalent bonding.

Chemical Properties:

clear colorless to slightly yellow liquid


HDT can be used to assemble monolayers on the surface of a substrate. When the substrate is exposed to a solution of HDT, the molecule spontaneously self-assembles and binds with the exposed atoms on the surface, creating a single monolayer of molecules. The HDT molecules form a dense, uniform monolayer, which provides a protective coating against physical and chemical damage.

HDT can also be used to covalently bond to the substrate surface. This requires a bit of extra work, as the HDT molecules must first be linked to the surface atoms in a certain manner. This process is called cross-linking and involves the use of a special cross-linking reagent that binds the HDT molecules to the substrate surface.

Chemical Properties

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Clear colorless to slightly yellow



Storage conditions:

Store in glass bottle

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