2,5-DICHLORO-4,6-DIMETHYLNICOTINONITRILE

Description:

2,5-Dichloro-4,6-dimethylnicotinonitrile (CAS No. 91591-63-8) is an organic compound with a wide range of applications in organic synthesis. Its white crystalline solid form has a melting point of 195 °C and a density of 1.38 g/cm3. This compound has two chlorine atoms and two nitrogen atoms in its structure, resulting in the molecular formula C8H6Cl2N2.

Chemical Properties:

White crystalline solid

Uses:

The synthesis of 2,5-dichloro-4,6-dimethylnicotinonitrile is a relatively simple process. It can be synthesized either by the reaction of 2,5-dibromo-4,6-dimethylnicotinonitrile with potassium thiocyanate or by the reaction of 2,5-dichloroacetophenone with 4,6-dimethylpyridine or 2-(methylthio)aniline in the presence of triethylamine base and chlorinated solvents such as dichloromethane. 

2,5-Dichloro-4,6-dimethylnicotinonitrile has a variety of uses in organic synthesis. It can be used as a catalyst in the synthesis of esters, amides, and nitriles. It can also be used as a reagent in the synthesis of a variety of heterocyclic compounds. In addition, it can be used as a reagent in the synthesis of polymeric materials such as polyurethanes and polyamides.