3,4,5-Trifluorophenylboronic acid is an organoboronic acid containing three fluorine atoms attached to the phenyl group. It is used as a reagent in organic synthesis and is considered a useful starting material for many types of reactions, such as Suzuki-Miyaura cross-coupling and Sonogashira–Hagihara cross-coupling. It is a versatile reagent that can be used in a variety of synthetic reactions, such as palladium-catalyzed cross-coupling reactions and Heck reactions.
3,4,5-Trifluorophenylboronic acid
143418-49-9
C6H4BF3O2
175.9
Description:
The chemical formula of 3,4,5-Trifluorophenylboronic acid is C6H4BF3O2. This compound has an aromatic ring structure with three fluorine atoms attached to a central carbon atom. The three fluorine atoms form a planar structure with the central carbon atom at the center, forming a trigonal bipyramid. The compound has a melting point of 290-295 °C, a boiling point of 263.6±50.0 °C, and a solubility of 18.43g/l in water.
Chemical Properties:
Tan Powder
Uses:
3,4,5-Trifluorophenylboronic acid is also used as a coupling reagent in the synthesis of organic compounds. This compound is capable of forming carbon-carbon bonds with various molecules, resulting in the synthesis of complex molecules. Additionally, this compound can be used as a catalyst in organic reactions.
In addition to its use as a coupling reagent, 3,4,5-Trifluorophenylboronic acid can also be used as a source of fluorine in various processes. This compound can be used in the synthesis of fluorinated compounds such as trifluorophenylmethyl bromide and trifluorophenylmethanol. Additionally, this compound is also used in the synthesis of pharmaceuticals, such as leflunomide, an immunosuppressant used to treat rheumatoid arthritis.
Chemical name: | 3,4,5-Trifluorophenylboronic acid |
|---|---|
Cas No: | 143418-49-9 |
Molecular Formula: | C6H4BF3O2 |
Formula Weight: | 175.9 |
Apperance: | Tan Powder |
Purity: | 98% |
Storage conditions： | Keep in dark place,Sealed in dry,Room Temperature |
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Tags: AKOSBRN-0138; 3,4,5-TRIFLUOROPHENYLBORONICACID; 3,4,5-TRIFLUOROBENZENEBORONICACID; 3,4,5-Trifluophenylboronicacid; 3,4,5-TrifluorobenzChemicalbookeneboronicacid97%; 3,4,5-Trifluorobenzeneboronicacid97%; 3,4,5-TRIFLUOROPHENYLBORONICACIDMIN96%HPLC; 3,4,5-TrifluorophenylboronicAicd
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