4-(dimethylamino)phenol

4-(Dimethylamino)phenol, CAS No 619-60-3, is a chemical compound with the molecular formula C8H11NO, and a molecular weight of 137.18. It is also known as 4-Dimethylaminophenol or Phenol, 4-(dimethylamino)-. Its boiling point is 260°C, melting point is 138-141°C, and its flash point is 136°C. It has a density of 1.1±0.1 g/cm3 and a refractive index of 1.5560 (estimate). It is used to manufacture neostigmine, a medication used to treat myasthenia gravis.

619-60-3

Chemical Name:

4-(dimethylamino)phenol

CAS No:

619-60-3

Molecular Fomula:

C8H11NO

Formula Weight:

137.18

Chemical Uses

Description:

4-(Dimethylamino)phenol (CAS No 619-60-3) is a chemical compound with the molecular formula C8H11NO and a molecular weight of 137.18. It is also known as Phenol, 4-(dimethylamino)- or 4-Dimethylaminophenol. It is a colorless to pale yellow crystalline solid with a strong, pungent odor. 

4-(Dimethylamino)phenol has a boiling point of 260°C, a melting point of 138-141°C, and a flash point of 136°C. It has a density of 1.1±0.1 g/cm3 and a refractive index of 1.5560 (estimate). It is soluble in methanol, ethanol, and chloroform and is slightly soluble in water.

Uses:

4-(Dimethylamino)phenol is primarily used in the manufacture of neostigmine, a medication used to treat myasthenia gravis. Neostigmine is an acetylcholinesterase inhibitor, meaning it prevents the breakdown of the neurotransmitter acetylcholine. This helps to improve muscle strength in people with myasthenia gravis. 

4-(Dimethylamino)phenol is also used in the production of dyes, inks, and photographic materials, as well as some pharmaceuticals. It can be used as an intermediate for the synthesis of other chemicals, including pharmaceuticals and agricultural chemicals.

Chemical Properties

Chemical name:

4-(dimethylamino)phenol

Cas No:

619-60-3

Molecular Formula:

C8H11NO

Formula Weight:

137.18 g/mol

EINECS:

210-604-8

Melting point

138-141℃

Boiling point

425.9±55.0 °C(Predicted)

Density

1.089

Refractive index

1.5560 (estimate)

Fp

136℃

Pka

10.11±0.13(Predicted)

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