Brexpiprazole

Brexpiprazole is an adjunctive antipsychotic drug used for the treatment of schizophrenia. It is a dopamine D2 receptor partial agonist and is known to have minimal effects on the concentration–time curve or pharmacokinetics of other antipsychotics. Brexpiprazole also does not cause extrapyramidal symptoms, which is a common side effect of many antipsychotics. Its chemical structure is identified as 913611-97-9.

913611-97-9

Chemical Name:

Brexpiprazole

CAS No:

913611-97-9

Molecular Fomula:

C16H12N2O

Formula Weight:

433.57

Chemical Uses

Description:

Brexpiprazole is an adjunctive antipsychotic drug used for the treatment of schizophrenia. It is a dopamine D2 receptor partial agonist, meaning it is able to interact with the dopamine receptors in the brain to provide therapeutic benefits, yet it has minimal effects on the concentration–time curve or pharmacokinetics of other antipsychotics. In addition, it does not cause extrapyramidal symptoms, which is a common side effect of many antipsychotics.

Uses:

Due to its unique chemical structure (identified as 913611-97-9), Brexpiprazole is a third generation antipsychotic, providing a more effective and safer alternative to other antipsychotic drugs. This means that patients can take lower doses than with other antipsychotics, but still gain the same therapeutic benefits. 

Brexpiprazole has also been well tolerated, with minimal side effects such as drowsiness and headache. Brexpiprazole has been found to be particularly beneficial in treating schizophrenia, as it is able to target the symptoms of the disorder more effectively than other antipsychotics. It is thought to be particularly effective in treating negative symptoms such as social withdrawal, lack of motivation, and emotional responsiveness. Additionally, its dopamine receptor partial agonist properties have also been demonstrated to improve cognitive functioning, making it an important tool for treating cognitive deficits in schizophrenia.

Chemical Properties

Chemical name:

Brexpiprazole

Cas No:

913611-97-9

Molecular Formula:

C25H27N3O2S

Formula Weight:

433.57 g/mol

EINECS

811-628-7

Boiling point

675.2±55.0 °C(Predicted)

Density

1.245±0.06 g/cm3(Predicted)

pka

11.22±0.70(Predicted)

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Tags: OPC-34712; Brexpiprazole impurity a; 7-[4-(4-(Benzo[b]thien-4-yl)-piperazin-1-yl)butoxy]-1H-quinolin-2-one; 7-{4-[4-(1-Benzothiophen-4-yl)piperazin-1-yl]butoxy}quinolin-2(1H)-one; 7-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one; CS-1678; Brexpiprazole; Epipiprazole860; Epipiprazole863; Epipiprazole864

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