Lefamulin (cas 1061337-51-6) is a semisynthetic pleuromutilin antibiotic that is used to treat bacterial pneumonia. It is derived from a natural compound called pleuromutilin, which is produced by a type of fungus found in soil.
Lefamulin
1061337-51-6
C28H45NO5S
507.73
Description:
Lefamulin is a semi-synthetic antibiotic drug used to treat bacterial infections. It belongs to the macrolide class of antibiotics and has a chemical formula of C28H45NO5S. Lefamulin has been shown to be effective against a wide range of Gram-positive and Gram-negative bacteria, including Streptococcus pneumoniae and Haemophilus influenzae.
Chemical Properties:
powder
Uses:
Lefamulin is typically used to treat bacterial pneumonia caused by certain strains of Streptococcus pneumoniae and Haemophilus influenzae. It is effective against both drug-resistant and drug-susceptible bacteria, and it is safe and well-tolerated in clinical studies.
Lefamulin is approved for the treatment of community-acquired bacterial pneumonia (CABP) caused by specific Streptococcus pneumoniae, Staphylococcus aureus, Haemophilus influenzae, and Klebsiella pneumoniae bacteria. It is also used to treat adult patients with acute bacterial skin and skin structure infections (ABSSSI) caused by Streptococcus pyogenes, Staphylococcus aureus, and other susceptible organisms.
Chemical name: | Lefamulin |
|---|---|
Cas No: | 1061337-51-6 |
Molecular Formula: | C28H45NO5S |
Formula Weight: | 507.73 |
Apperance: | Powder |
Purity: | 98% |
Storage conditions： | Store at low temperature and avoid light. |
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tags: Lefamulin; 2-[[(1R,2R,4R)-4-Amino-2-hydroxycyclohexyl]thio]acetic acid (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester; BC 3781;Lefamulin(BC-3781); Acetic acid, 2-[[(1R,2R,4R)-4-amino-2-hydroxycyclohexyl]thio]-, (3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-yl ester
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