Roflumilast

Roflumilast is a drug used to treat chronic obstructive pulmonary disease (COPD) and asthma. It belongs to a class of medications known as phosphodiesterase-4 (PDE4) inhibitors. Roflumilast works by blocking the action of an enzyme called phosphodiesterase-4, which is responsible for the breakdown of certain chemicals in the body that can cause inflammation.

162401-32-3

Chemical Name:

Roflumilast

CAS No:

162401-32-3

Molecular Fomula:

C17H14Cl2F2N2O3

Formula Weight:

403.21

Chemical Uses

Description:

Roflumilast is believed to have a unique mechanism of action, in that it works by inhibiting the release of inflammatory mediators such as leukotrienes and prostaglandins that contribute to COPD symptoms. This inhibition of the release of these mediators can reduce the intensity of COPD symptoms such as breathlessness, coughing, and wheezing. 

Chemical Properties:

white to beige powder

Uses:

Roflumilast has been used in a number of clinical trials to assess its safety and effectiveness in the treatment of COPD. The results of these trials suggest that roflumilast can improve lung function and reduce the frequency of exacerbations in people with COPD. Additionally, it has been found to be well-tolerated by most patients, with few serious side effects.

Roflumilast has been approved for the treatment of COPD in some countries, but further research is needed to determine its efficacy in other respiratory conditions. Additionally, clinical trials are ongoing to evaluate its potential for treating other diseases, including asthma, cystic fibrosis, and idiopathic pulmonary fibrosis.

Chemical Properties

Chemical name:

Roflumilast

Cas No:

162401-32-3

Molecular Formula:

C17H14Cl2F2N2O3

Formula Weight:

403.21

Apperance:

white to beige powder

Purity:

99%

Storage conditions:

Store at -20°C.

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Tags: ROFLUMILAST; 3-(Cyclopropylmethoxy)-N-(3,5-dichloro-4-pyridinyl)-4-(difluoromethoxy)benzamide;B9302-107; BY217;BYK20869; Daxas; Roflumilast/3-(cyclopropChemicalbookylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide; 3-(Cyclopropylmethoxy)-N-(3,5-dichloropyridin-4-yl)-4-(difluoromethoxy)benzamide

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