Ruxolitinib is a small molecule kinase inhibitor that is used to treat a variety of conditions, including myelofibrosis and polycythemia vera. Ruxolitinib, also known as Jakafi, is a Janus kinase (JAK) inhibitor that works by blocking a signal in the body that causes cells to grow and divide. Ruxolitinib has also been used in clinical trials to treat other conditions, such as psoriasis, graft-versus-host disease, and certain types of leukemia.
Ruxolitinib
941678-49-5
C17H18N6
306.37
Description:
Ruxolitinib is a prescription medication used to treat myelofibrosis, a rare disorder characterized by excess scarring of the bone marrow. It is also sometimes prescribed off-label to treat certain types of leukemia. Ruxolitinib is a member of the Janus Kinase (JAK) inhibitor class of drugs, which are used to reduce the production of certain proteins that can cause inflammation.
Chemical Properties:
White powder
Uses:
Ruxolitinib is a new type of medication for treating myelofibrosis, a disorder caused by the bone marrow producing too much scar tissue. Normally, bone marrow produces stem cells that go on to form the red blood cells, white blood cells, and platelets that are responsible for carrying oxygen and fighting infection. In patients with myelofibrosis, the bone marrow produces an excess amount of scar tissue, which can prevent or reduce the production of these essential blood cells, leading to anemia, fatigue, and increased risk of infection.
Chemical name: | Ruxolitinib |
|---|---|
Cas No: | 941678-49-5 |
Molecular Formula: | C17H18N6 |
Formula Weight: | 306.37 |
Apperance: | White powder |
Purity: | 99% |
Storage conditions： | Store at -20°. |
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Tags: (R)-3-(4-(7H-Pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile; (betaR)-beta-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazole-1-propanenitrile; (3R)-3-(4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-1H-pyrazol-1-yl)-3-Chemicalbookcyclopentylpropanenitrile; (3R)-3-cyclopentyl-3-(4-{7H-pyrrolo[2,3-d]pyriMidin-4-yl}-1H-pyrazol-1-yl)propanenitrile; INCB018424(Ruxolitinib); Jakafi;Roxolitinib; β-Cyclopentyl-4-(7H-pyrrolo[2,3-d]pyriMidin-4-yl)-(βR)-1H-pyrazole-1-propanenitrile
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